Galleria mellonellaas a model host to studyParacoccidioides lutziiandHistoplasma capsulatum
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چکیده
منابع مشابه
Developing Galleria mellonella as a model host for human pathogens
The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be establi...
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Candida species are common human fungal pathogens causing a wide range of clinical diseases, ranging from superficial infections to life-threatening systemic disease. Superficial infections include vaginal candidiasis which affects over 75% of women during their lifetime with 5% of women suffering debilitating recurrent infections. Life-threatening systemic Candida disease is the fourth most co...
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Candida spp. are among the most important human fungal pathogens, with infections ranging from relatively benign, superficial manifestation to life-threatening deep-seated candidiasis and disseminated disease. Different mouse models have been developed to recapitulate the different forms of candidiasis and murine models are considered to be the gold standard to study pathogenesis and analyze ef...
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Histoplasma capsulatum is a pathogenic fungus that has caused infections in all continents except Antarctica although most disease is found within the Americas. It produces a broad spectrum of illness that can on occasion be fatal. Understanding the interaction between the host and the fungus provides insights into the pathogenic mechanisms as well as the host response to replicating fungi. Thi...
متن کاملGalleria mellonella as a model host to study gut microbe homeostasis and brain infection by the human pathogen listeria monocytogenes.
The gastrointestinal tract in both mammals and insects is associated with microbes (collectively the microbiota), which are controlled by the intestinal immune system. These microbes regulate pathogens that can infect gut epithelial cells, and there is increasing evidence for a reciprocal relationship between beneficial and pathogenic bacteria in the gut and the intestinal immune system. Deciph...
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ژورنال
عنوان ژورنال: Virulence
سال: 2013
ISSN: 2150-5594,2150-5608
DOI: 10.4161/viru.23047